Place Category: Member
“Cantacuzino” National Military-Medical Institute for Research-Development is the main technical and scientific medical unit within the Ministry National of Defence and Ministry of Health involved in the development and application of programs aiming at preventing and controlling infectious diseases.
It was officially founded in 1921 by Prof. Ioan I. Cantacuzino who since 1901, when he was appointed to a professorship at the Faculty of Medicine in Bucharest and founded the “Experimental Medicine Laboratory”, had been co-ordinator of a team of researchers.
Main fields of activity:
- Basic and applicative research in microbiology and immunology;
- Production of vaccines, bacterial immunomodulators, diagnostic reagents, bacteriological and cell culture media;
- Microbiological surveillance by the National Reference Centers recognized by the Ministry of Health for diagnosis and surveillance of communicable diseases;
- Services of technical and methodological consulting granted to all profile units across the country, expertise, participation in national and international epidemiological surveillance networks;
- Teaching activities;
- Laboratory investigations for health insurances companies, population and different other units;
- Breeding and marketing of laboratory animals.
The activities in „Cantacuzino” are developed in three main centers: the Center for Advanced Studies, the National Expertise Center in Medical Microbiology and the National Center for Biological Products.
The institute is a member of the International Network of Pasteur Institutes.
The activities in the project a centered on three main research groups of the institutes: Viral Respiratory Diseases Laboratory, Infection and Immunity Laboratory and Cellular Immunology Laboratory.
The Viral respiratory diseases laboratory is involved in research and public health activities related viral respiratory diseases. Part of its activity is focused on influenza virus research and surveillance. Influenza National Center located in this laboratory performs national influenza surveillance through a sentinel type system being accredited by WHO (www.who.int/csr/disease/influenza/Centers/en/) and is part of international and European surveillance systems and member in the European Influenza Surveillance Scheme (EISS –www.eiss.org).
Research and public health projects. Technological background includes influenza virus detection and typing by different methods including real time PCR and sequencing.
Infection and Immunity Laboratory has the main research interest is the study of immune response modulation by bacterial and viral components. One of the main streams of the research is the involvement of cytokines as main mediators of immune response in different pathologies (microbial induced, cardiovascular, cancer etc). Modern techniques are focused in the simultaneous detection of the cytokines based on a modern multiplex system.
Cellular Immunology Laboratory reaches program is focused on T lymphocytes mediated autoimmune disease. One of the remarkable model developed in the laboratory are the transgenic mouse strains allowing major advances in the understanding of the mechanisms involved in the breakdown of immune self-tolerance and in islet destruction and the investigation of the pathogenic mechanisms which will be used for monitoring and optimization of different therapeutic approach. The laboratory has developed a platform of cellular immunology studies including cell stimulation and proliferation, immunophenotyping by flow cytometry, etc.
Institute contacts Name Contact email Representative Filip Alexandru Vladimirescu email@example.com Institute Representative Adrian Onu Adrian.Onu@cantacuzino.ro Institute Representative Monica Straut firstname.lastname@example.org Scientific Representative Ani Ioana Cotar email@example.com Scientific Representative