Lovisenberggata 6, Oslo, Oslo, Norway

Houtribweg 39, Lelystad, Flevoland, The Netherlands

3721 Utrecht Court, Christchurch, England, United Kingdom

Uppsala, Sweden

Stockholm, Sweden

Uppsala, Sweden

Teramo, Abruzzo, Italy

Bettola-Zeloforomagno, Lombardy, Italy

Viale Regina Elena, Rome, Lazio, Italy

Südufer 10, Greifswald, Mecklenburg-Vorpommern, Germany

Max-Dohrn-Straße 8, Berlin, Berlin, Germany

Waterloo Road, London Borough of Lambeth, England, United Kingdom

Reigate Road, Reigate and Banstead, England, United Kingdom

Campus-Vienna-Biocenter 191, Vienna, Wien, Austria

Anker Engelunds Vej 1, Stampen, Region Hovedstaden, Denmark

Rue Juliette Wytsman - Juliette Wytsmanstraat 14, Ixelles - Elsene, Région de Bruxelles-Capitale - Brussels Hoofdstedelijk Gewest, Belgium

OHEJP Cohesive project logo

The Project #COHESIVE

Start: 1 January 2018
Duration: 3 Years
Domain: Integrative Activity
Keywords: Common reporting, and signalling procedures, joint platform for sharing surveillance data and their interpretation, incl. risk assessments
Contact: Kitty Maassen (RIVM)

COHESIVE: One Health Structure In Europe.

The aims of COHESIVE project were to develop sustainable One Health approaches with respect to surveillance, signalling, assessing and controlling zoonoses at the national and regional level within EU countries and across borders.

Working towards a world with less zoonotic disease burden requires collaboration at all levels and between the veterinary and human domain. In some European countries, risk analysis structures to deal with (emerging) zoonoses in an integrated human‐veterinary setting have already been implemented. However, these structures mostly were implemented after experiencing one or more large outbreaks such as BSE in the UK or Q‐fever in The Netherlands. Now, these countries experience the advantages of integrated One Health approaches to deal with (re‐)emerging zoonoses, including AMR and food‐borne zoonoses.

Due to the very different organisation of food production systems, the veterinary and human health domains, both in and between countries, it must be realized that there is no general blue‐print for a OH risk‐analysis structure. In this context, the COHESIVE project was created with the aims to strengthen/improve (structured) collaboration between the human and veterinary domain in the area of risk‐analysis of (emerging) zoonoses in European Member States. It worked to achieve these aims by:

  1. Stimulating One Health approaches at the national level within EU countries (EJP partner member states) and focusing on strengthening human‐veterinary collaboration by designing common procedures and tools while taking into account similarities and differences between countries. Importantly, the project facilitated creating support for a One Health structure by organizing local workshops with national stakeholders.
  2. Devising a roadmap towards an EU zoonoses risk‐assessment of risk‐analysis structure. It brought together existing risk analysis and epidemiological tools, skills and facilities that are required for a ‘one‐health’ surveillance over member states borders, including exploration of the use and possible implementation of early warning systems across Europe.
  3. Designing and testing a common open source platform for the collection and analysis of surveillance and outbreak data on (foodborne) zoonoses. Thus providing IT tools and data that are quickly available, usable and helpful in outbreak situations and for risk assessments. The project focused on establishing, harmonising and improving tools for tracing, WGS and standardized risk assessments. Interoperability with the main data exchange systems at EU level were ensured such as the TESSy platform and the EFSA zoonoses data collection system. The COHESIVE project has now developed a website with guidelines for setting up a One Health Risk Analysis System (OHRAS) for signalling, assessing and controlling zoonoses in European countries:
  4. Capacity building within and between EU countries at several levels (executive level, communication, policy makers) within the area of zoonotic diseases. Several pilots, within and between countries, tested the developed tools (guidelines for setting‐up a ‘One Health Structure’, risk‐assessment tool, early warning tool, data platform) within country through specific Vet‐Med partnerships. Multiple member states and Vet‐Med partnership assessed the developed tools collectively on combined country surveillance. The COHESIVE project developed guidelines for risk analysis of zoonoses.

Project Outputs and Outcomes

A website with guidelines for setting up a One Health Risk Analysis System (OHRAS) for signalling, assessing and controlling zoonoses and its implementation in European countries (shown in the images at the bottom of this page). The OHRAS has been used by the following countries: Norway, Portugal, Belgium, Denmark, Sweden, Germany and France.

Four IT tools to support outbreaks and risk-based surveillance:

  1. The COHESIVE Decision Support Tool for One-Health Risk Assessment provides a broad introduction to the field of risk assessment. It classifies different risk assessment approaches against criteria such as timescale, geographical location or level of expertise. It also provides One Health and sector-specific examples of these approaches for further research.
  2. The COHESIVE Information System (CIS) is database and web-based interface designed to help integrate pathogen information from medical and veterinary sectors, beneficial for outbreak investigation and surveillance.
  3. FoodChain-Lab web application (FCL Web) enables the reliable tracing of a specific food product along the food supply chain during a foodborne disease incident.
  4. Shiny Rrisk is a web-based tool for risk assessment using Monte-Carlo Simulation and helps to build quantitative risk models via a user-friendly shiny surface including uncertainty analysis.

More information on COHESIVE outputs can be found here.

Read more about COHESIVE project outcomes and impacts in an interview with Project Leader, Kitty Maassen, published on the RIVM website in October 2022.

Overall, specific COHESIVE resources can be used to facilitate international coordination, improve the efficiency of One Health risk analyses and benefit pandemic disease preparedness.

The COHESIVE project has developed a website with guidelines for setting up a One Health Risk Analysis System (OHRAS) for signalling, assessing and controlling zoonoses in European countries.

For more information, see the three infographics above: Why, What, and How.

Visit the website to access the guidelines:

Project Assets

Mangone, I., Radomski, N., Di Pasquale, A., Santurbano, A., Calistri, P., Cammà, C., Maassen, K. (2021). Refinement of the COHESIVE Information System towards a unified ontology of food terms for the public health organizations. IFOW 2021 Integrated Food Ontology Workshop, September 15-18, 2021, Bolzano Italy. DOI: & DOI:

Dewar, R., Gavin, C., McCarthy, C., Taylor, R A., Cook, C., Simons, R R L. (2021). A user-friendly decision support tool to assist one-health risk assessors. One Health, 13, 100266. DOI:

Buschhardt, T., Günther, T., Skjerdal, T., Torpdahl, M., Gethmann, J., Filippitzi, M. E., Maassen, C., Jore, S., Ellis-Iversen, J., Filter, M. (2021). A one health glossary to support communication and information exchange between the human health, animal health and food safety sectors. One Health. 13, 100263. DOI:

D1.1-Kick off meeting

D1.3-Annual Meeting 2019

D1.4-Annual report 2019

D1.5 Annual meeting 2020

D1.7 Closing symposium

D1.8 – Annual report 2020


D2.2-Inventory and ambition workshop

D2.4-Thematic workshops

D2.5 – Development of common procedures and tools

D2.6 – Pilots performed in Norway and Portugal on the roadmap of the One Health risk analysis guidelines described in D2.5

D3.1-Inventory and ambition workshop

D3.2-Thematic Workshops

D3.4 – Inventory and analysis of tools for horizon scanning

D3.5-Retrospective Systems Mapping Detection of Outbreaks

D3.6 – B. canis in Europe: Gaps and challenges in controlling the spread

D3.7 – Drivers of change in One Health – a Horizon scanning exercise

D3.8-Review Economic Analysis Foodborne Zoonoses

D4.1-Implemented database

D4.1.2-Description of the links and the linked databases

D-4.1.3-Databases containing the country data

D4.1.4-Description of the pipelines implemented to feed the analysis tools with the data stored in the three databases of the COHESIVE project

D4.2.2-FoodChain‐Lab with integrated network analysis module as a web‐service, browser‐ready, open source and implemented in the BfR cloud

D4.2.3-Integration of surveillance and outbreak data into the software platform

D4.4.1 – Dissemination activities on Data platform to facilitate risk‐analysis and outbreak control

D4.5-Report of available tools and algorithms and ranking of most valuable features


Project Events

COHESIVE End Symposium- 8th-10th November 2021

Brucella canis workshop 18th May 2021

COHESIVE General Meeting 27th-29th November 2019

COHESIVE Annual Meeting 10th-12th April 2019

COHESIVE Workshop 26th-27th November 2018. Read of its success here!



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